Endocrine Abstracts

Introduction and aim: Cytokines play a crucial role in modulating immune response in both Hashimoto’s thyroiditis (HT) and Graves’ disease (GD). They may contribute to drive the autoimmune response skewing toward the Th17 phenotype and away from Th1 or Th2 phenotypes. Recent studies revealed an essential role of Th17 cells and their cytokines in the development of autoimmune thyroid diseases (AITD). However, participation of Th17 cells in the pathogenesis of GD is ...